Lag luam wholesale Ntshiab Ntuj Atractylodes Lancea Roj rau Txhua Hnub Kev Lag Luam Tshuaj Tshuaj Ntsuab Extract Atractylis Roj

pisthorchis viverrini (OV)-induced cholangiocarcinoma (CCA) yog mob qog noj ntshav ntawm txiv neej thiab poj niam, tshwj xeeb tshaj yog nyob rau Thaib teb. Cov kev tshawb fawb tsis ntev los no tau nthuav tawm tias ethanol extract ntawm AL tau ua rau muaj kev cuam tshuam rau OV-vim CCA tsiaj qauv yam tsis muaj tshuaj lom los ntawm kev tswj hwm qhov ncauj rau 30 hnub raws li cov txiaj ntsig tau los ntawm positron emission tomography-xws li tomography thiab txiv neej Syrian hamsters [7]. Txhawm rau tshawb nrhiav cov txiaj ntsig ntawm AL rhizome ntawm lub plab zom mov, cov tshuaj atropine-, dopamine-, thiab 5-hydroxytryptamine (5-HT)-kho nas tau txais hauv txoj kev tshawb no. Cov txiaj ntsig tau hais tias 1 mg / kg extract tuaj yeem cuam tshuam dopamine-induced gastric emptying thiab gastrointestinal motility txo los ntawm intraperitoneal txhaj. Cov extract ntawm qhov concentration ntawm 1000 mg / kg yuav txwv tsis pub atropine-induced plab hnyuv motility txo, thiab cov extract ntawm 500 mg / kg koob yuav thaiv 5-HT-induced gastric emptying thiab me me plab hnyuv motility txo [8]. Tsis tas li ntawd, AL tau tawm dag zog los tiv thaiv lub plab ulcer hauv cov qauv nas los ntawm kev txo qis cov neeg kho mob (piv txwv li qog necrosis factor-α (TNF-α), interleukin-8 (IL-8), IL-6), thiab prostaglandin E2 (PGE2) thiab nce epidermal growth factor (EGF) thiab trefoil factor2 (TFF2) [9]. Av-borne fungal pathogens txo 30% yields ntawm peanuts [10]. Tsis ntev los no, nws tau tshaj tawm tias cuam tshuam nrog cov txiv laum huab xeeb, AL tuaj yeem tiv thaiv cov kab mob hauv av los ntawm kev cuam tshuam ntawmFusarium oxysporumkev loj hlob [11]. Petroleum ether (PE) rho tawm los ntawm AL pom tias muaj kev cuam tshuam rau BGC-823 thiab SGC-7901 tib neeg lub plab zom mov. PE feem yuav ua rau apoptosis, cell voj voog ntes, thiab mitochondrial transmembrane tej zaum yuav hloov [12]. Ib daim ntawv tshaj tawm tsis ntev los no tau hais tias MeOH extract ntawm AL tuaj yeem tiv thaiv nitric oxide (NO) ntau lawm hauv lipopolysaccharide-stimulated murine macrophage-zoo li RAW264.7 hlwb thiab induce granulocyte-colony stimulating factor (G-CSF) secretion hauv murine normal colonic epithelial MCE301 cells. TSIS yog ib qho dawb radical [13]. Cov ethanol extract ntawm AL exerted ib qho tseem ceeb inhibitory nyhuv ntawm lipase nrog IC50 9.06 µg / mL nyob rau hauv ib tug tib neeg pancreatic lipase assay, thiab nthuav tawm cov nyhuv los tiv thaiv kev rog ntawm kev noj cov zaub mov uas muaj rog rog-vim cov nas rog rog ntawm qhov siab ntawm 500 mg. /kg [14]. Cov dej rho tawm los ntawm AL tau qhia txog kev tawm tsam tawm tsam serotonin receptors thiab cov nyhuv inhibitory ntawm kev xaiv 5-HT2A / 2C agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane-induced lub taub hau-twitch teb hauv cov nas. [15]. Cov dej rho tawm los ntawm AL txo qis triptolide-induced toxicity los ntawm kev txo qis ntawm cov kab mob siab ntawm CYP3A. Nyob rau lub sijhawm no, AL tuaj yeem txhim kho cov tshuaj tiv thaiv kab mob ntawm triptolide. Cov kev tshawb pom no tau pom tias AL tuaj yeem cuam tshuam toxicity thiab nce kev kho mob ntawm triptolide los ntawm kev sib xyaw ua ke