Cov roj ntshiab ntuj Artemisia Annua rau kev kho mob

piav qhia luv luv:

Vim muaj cov tshuaj tshwj xeeb sesquiterpene endoperoxide lactone artemisinin (Qinghaosu), yog ib qho tshuaj tseem ceeb tshaj plaws los ntawm cov nroj tsuag hauv kev kho mob chloroquine-resistant thiab cerebral malarias, cov nroj tsuag no tau cog rau ntawm qhov loj hauv Suav teb, Nyab Laj, Qaib ntxhw, Iran, Afghanistan, thiab Australia. Hauv Is Nrias teb, nws tau cog rau ntawm qhov kev sim hauv thaj chaw Himalayan, nrog rau cov huab cua sov thiab subtropical [3].

Cov roj tseem ceeb uas muaj ntau mono- thiab sesquiterpenes sawv cev rau lwm qhov chaw muaj txiaj ntsig zoo rau kev lag luam [4]. Dhau li ntawm qhov sib txawv tseem ceeb hauv nws feem pua ​​​​thiab cov khoom xyaw tau tshaj tawm, nws tau ua tiav rau ntau txoj kev tshawb fawb uas feem ntau txhawj xeeb txog kev ua haujlwm antibacterial thiab antifungal. Ntau yam kev tshawb fawb sim tau tshaj tawm txog niaj hnub no siv ntau txoj kev sib txawv thiab sim cov kab mob sib txawv; yog li ntawd, kev sib piv kev tshuaj xyuas ntawm qhov ntau thiab tsawg yog qhov nyuaj heev. Lub hom phiaj ntawm peb qhov kev tshuaj xyuas yog los sau cov ntaub ntawv ntawm kev ua haujlwm antimicrobial ntawmA. annuacov volatiles thiab nws cov khoom tseem ceeb los pab txhawb rau yav tom ntej ntawm kev sim microbiological hauv daim teb no.

2. Kev Faib Tawm ntawm Cov Nroj Tsuag thiab Cov Qoob Loo ntawm Cov Volatiles

Cov roj tseem ceeb (cov roj uas yaj tau) ntawmA. annuatuaj yeem ncav cuag cov qoob loo ntawm 85 kg / ha. Nws yog synthesized los ntawm cov hlwb secretory, tshwj xeeb tshaj yog ntawm qhov saum toj kawg nkaus ntawm cov nroj tsuag (sab saum toj 1/3 ntawm kev loj hlob thaum loj hlob) uas muaj yuav luag ob npaug ntawm tus lej yog tias piv nrog cov nplooj qis. Nws tau tshaj tawm tias 35% ntawm cov nplooj ntoo loj hlob yog them nrog capitate glands uas muaj cov khoom terpenoidic volatile. Cov roj tseem ceeb los ntawmA. annuatau faib tawm, nrog rau 36% ntawm tag nrho los ntawm peb feem peb sab saud ntawm cov nplooj, 47% los ntawm peb nruab nrab, thiab 17% los ntawm peb feem peb qis, nrog tsuas yog cov nyiaj me me hauv cov qia tseem ceeb thiab cov hauv paus hniav. Cov roj ntau ntawm cov roj feem ntau yog nyob nruab nrab ntawm 0.3 thiab 0.4% tab sis nws tuaj yeem ncav cuag 4.0% (V / W) los ntawm cov genotypes xaiv. Ntau txoj kev tshawb fawb tau tso cai rau qhov xaus lus tiasA. annuacov qoob loo yuav tsum tau sau ua ntej pib tawg paj kom tau txais cov qoob loo ntau ntawm artemisinin thiab cov qoob loo yuav tsum tau tso cai rau kev loj hlob kom tau txais cov roj tseem ceeb ntau [5,6].

Cov qoob loo (cov tshuaj ntsuab thiab cov roj tseem ceeb) tuaj yeem nce ntxiv nrog cov nitrogen ntxiv thiab qhov kev loj hlob zoo tshaj plaws tau txais nrog 67 kg N / ha. Kev nce qhov ceev ntawm cov nroj tsuag feem ntau ua rau cov roj tseem ceeb tsim ntau ntxiv ntawm thaj chaw, tab sis cov roj tseem ceeb siab tshaj plaws (85 kg roj / ha) tau ua tiav los ntawm qhov ceev nruab nrab ntawm 55,555 nroj tsuag / ha tau txais 67 kg N / ha. Thaum kawg hnub cog thiab lub sijhawm sau qoob loo tuaj yeem cuam tshuam rau qhov siab tshaj plaws ntawm cov roj tseem ceeb tsim tawm [6].

3. Cov Qauv Tshuaj Lom Zem ntawm Cov Roj Tseem Ceeb

Cov roj tseem ceeb, feem ntau tau los ntawm kev hydrodistillation ntawm cov paj saum toj kawg nkaus, soj ntsuam nrog GC-MS, tau qhia txog qhov sib txawv loj heev hauv cov khoom sib xyaw zoo thiab ntau npaum li cas.

Cov qauv tshuaj feem ntau cuam tshuam los ntawm lub caij sau qoob loo, chiv thiab pH ntawm cov av, kev xaiv thiab theem ntawm kev ziab, qhov chaw nyob, chemotype lossis subspecies, thiab kev xaiv ntawm ib feem ntawm cov nroj tsuag lossis genotype lossis txoj kev rho tawm. Hauv Rooj1, cov khoom tseem ceeb (> 4%) ntawm cov qauv tshawb nrhiav tau tshaj tawm.

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