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100% Cov Roj Ntuj Ntshiab Eucommiae Foliuml Cov Roj Tseem Ceeb Rau Kev Saib Xyuas Tawv Nqaij

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Eucommia ulmoides(EU) (feem ntau hu ua "Du Zhong" hauv lus Suav) koom nrog tsev neeg Eucommiaceae, ib hom ntoo me me uas nyob hauv Central China [1]. Cov nroj tsuag no tau cog dav hauv Suav teb vim nws qhov tseem ceeb rau kev kho mob. Muaj li ntawm 112 lub tebchab tau raug rho tawm los ntawm EU uas suav nrog lignans, iridoids, phenolics, steroids, thiab lwm yam tebchab. Cov tshuaj ntsuab ntxiv ntawm cov nroj tsuag no (xws li tshuaj yej qab) tau qhia txog qee yam khoom siv kho mob. Cov nplooj ntawm EU muaj kev ua haujlwm siab dua ntsig txog cortex, paj, thiab txiv hmab txiv ntoo [2,3]. Cov nplooj ntawm EU tau raug tshaj tawm tias yuav ua rau cov pob txha muaj zog thiab cov leeg nqaij ntawm lub cev muaj zog [4], yog li ua rau tib neeg muaj sia nyob ntev thiab txhawb kev muaj menyuam [5]. Cov tshuaj yej qab qab uas ua los ntawm nplooj ntawm EU tau tshaj tawm tias yuav txo cov rog thiab txhim kho kev ua haujlwm ntawm lub cev. Cov tshuaj Flavonoid (xws li rutin, chlorogenic acid, ferulic acid, thiab caffeic acid) tau tshaj tawm tias muaj cov tshuaj antioxidants hauv nplooj ntawm EU [6].

Txawm hais tias muaj cov ntaub ntawv txaus txog cov khoom phytochemical ntawm EU, tab sis muaj ob peb txoj kev tshawb fawb txog cov khoom pharmacological ntawm ntau yam tshuaj uas tau rho tawm los ntawm cov tawv ntoo, noob, qia, thiab nplooj ntawm EU. Daim ntawv tshuaj xyuas no yuav piav qhia cov ntaub ntawv ntxaws txog ntau yam tshuaj uas tau rho tawm los ntawm ntau qhov chaw (tawv ntoo, noob, qia, thiab nplooj) ntawm EU thiab kev siv cov tshuaj no rau hauv cov khoom noj khoom haus nrog cov pov thawj tshawb fawb thiab yog li muab cov ntaub ntawv siv rau kev siv EU.


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  • Kev Muaj Peev Xwm Muab Khoom:10000 Daim / Daim Ib Hlis
  • Cov Khoom Qhia Txog Khoom

    Cov Cim Npe Khoom

    Lignans thiab lawv cov derivatives yog cov khoom tseem ceeb ntawm EU [7]. Txog niaj hnub no, muaj 28 hom lignans (xws li bisepoxylignans, monoepoxylignans, neolignans, thiab sesquilignans) tau raug rho tawm ntawm cov tawv ntoo, nplooj, thiab noob ntawm EU. Iridoid glycoside, ib chav kawm ntawm cov metabolites theem nrab, yog qhov tseem ceeb thib ob ntawm EU. Iridoids feem ntau pom muaj nyob rau hauv cov nroj tsuag hu ua glycosides. Nees nkaum plaub iridoids tau raug rho tawm thiab txheeb xyuas los ntawm EU (Rooj 1). Cov tshuaj sib cais no suav nrog geniposidic acid, aucubin, thiab asperuloside uas tau tshaj tawm tias muaj cov khoom siv tshuaj dav dav [8–10]. Ob lub tshuaj tshiab ntawm iridoids, Eucommides-A thiab -C, nyuam qhuav raug rho tawm. Ob lub tshuaj ntuj no raug suav hais tias yog cov sib xyaw ntawm iridoid thiab amino acids. Txawm li cas los xij, txoj hauv kev uas lawv ua haujlwm tsis muaj [11].

    2.2. Cov Tshuaj Phenolic

    Cov tshuaj phenolic uas tau los ntawm cov khoom noj tau raug tshaj tawm tias muaj txiaj ntsig zoo rau tib neeg kev noj qab haus huv [12,13]. Kwv yees li 29 cov tshuaj phenolic tau raug rho tawm thiab txheeb xyuas los ntawm EU [14]. Tag nrho cov ntsiab lus ntawm cov tshuaj phenolic (hauv gallic acid sib npaug ntawm txhua cov extracts) tau raug tshuaj xyuas siv Folin-Ciocalteu phenol reagent. Cov teebmeem ntawm kev hloov pauv ntawm lub caij nyoog rau cov ntsiab lus ntawm qee cov tshuaj thiab cov antioxidants tau raug tshaj tawm. Hauv tib lub xyoo, cov ntsiab lus siab dua ntawm phenolics thiab flavonoids tau pom nyob rau hauv nplooj ntawm EU thaum Lub Yim Hli thiab Tsib Hlis, raws li. Rutin, quercetin, geniposidic acid, thiab aucubin muaj nyob rau hauv qhov concentration ntau dua thaum Lub Tsib Hlis lossis Lub Rau Hli [15]. Ntxiv mus, kev ua haujlwm siab dua ntawm 1,1-diphenyl-2-picrylhydrazyl (DPPH) kev ua haujlwm scavenging radical thiab lub peev xwm hlau ion chelating tau pom nyob rau hauv nplooj ntawm EU sau thaum Lub Yim Hli. Cov ntsiab lus ntawm cov khoom noj antioxidants kuj tau tshaj tawm hauv lub Tsib Hlis thaum piv rau lwm lub sijhawm ntawm lub xyoo [15]. Cov nplooj ntawm EU tau pom tias yog ib qho chaw nplua nuj ntawm cov aminoacids, cov vitamins, cov zaub mov, thiab flavonoids xws li quercetin, rutin, thiab geniposidic acid [11,16]. Tag nrho 7 flavonoids tau raug rho tawm los ntawmEucommiacov nroj tsuag [17]. Rutin thiab quercetin yog cov flavonoids tseem ceeb tshaj plaws [18]. Flavonoids yog cov tshuaj tseem ceeb uas muaj nyob rau hauv xwm thiab raug suav hais tias yog cov metabolites theem nrab thiab ua haujlwm ua cov tshuaj xa xov, cov neeg tswj kev ua haujlwm ntawm lub cev, thiab cov tshuaj tiv thaiv lub voj voog ntawm lub hlwb.

    2.3. Cov tshuaj steroids thiab Terpenoids

    Muaj rau hom tshuaj steroids thiab tsib hom terpenoids tau raug rho tawm thiab muab faib ua pawg los ntawm EU. Cov no suav nrogβ-sitosterol, daucosterol, ulmoprenol, betalin, betulic acid, ursolic acid, eucommidiol, rehmaglutin C, thiab 1,4α,5,7α-tetrahydro-7-hydroxymethyl-cyclopenta[c]pyran-4-carboxylic methyl ester uas tau cais tawm tshwj xeeb los ntawm cov tawv ntoo ntawm EU [19]. Loliolide kuj tau raug rho tawm ntawm nplooj [20].

    2.4. Cov Polysaccharides

    Cov polysaccharides los ntawm EU rau 15 hnub ntawm qhov concentration ntawm 300–600 mg/kg tau tshaj tawm tias muaj cov txiaj ntsig tiv thaiv raum raws li pom los ntawm malonaldehyde thiab glutathione theem tom qab perfusions raum [21]. Kev kuaj mob histological kuj qhia tau tias muaj cov khoom tiv thaiv kab mob antioxidant. Cov kua txiv hmab txiv ntoo los ntawm cov tawv ntoo ntawm EU siv 70% ethanol kuj qhia tau tias muaj kev tiv thaiv kab mob cadmium ntawm 125–500 mg / kg [22]. Kev kuaj mob histological kuj qhia tau tias EU ua ke nrogPanax pseudoginsengntawm 25% thiab 50% qhov hnyav, raws li, rau rau lub lis piam ntawm tus nqi ntawm 35.7–41.6 mg / kg muaj cov teebmeem tiv thaiv lub teeb rau ntawm glomerular filtration rate [8]. Ob lub polysaccharides tshiab tau raug cais tawm ntawm EU, uas yog eucomman A thiab B [23].

    2.5. Lwm Cov Khoom Xyaw thiab Cov Tshuaj

    Cov amino acids, microelements, vitamins, thiab fatty acids kuj tau raug rho tawm ntawm EU [17,21–23]. Sun et al. kuj tau tshawb pom cov tshuaj tshiab xws li n-octacosanoic acid, thiab tetracosanoic-2,3-dihydroxypropylester los ntawm EU [24].

    Cov roj fatty acid uas muaj nyob hauv cov roj uas tau rho tawm los ntawm cov noob ntawm EU tau qhia txog ntau yam sib txawv ntawm cov roj polyunsaturated xws li linoleic acid, linolenic acid (56.51% ntawm tag nrho cov roj fatty acids, TFAs), thiab linolelaidic acid (12.66% ntawm TFAs). Lub caij no, cov roj monounsaturated tseem ceeb uas tau rho tawm los ntawm cov noob tau pom tias yog isoleic acid (15.80% ntawm TFAs). Cov roj saturated tseem ceeb uas tau rho tawm suav nrog palmitic acid thiab stearic acid uas sawv cev rau 9.82% thiab 2.59% ntawm TFAs, feem.








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