100% Ntshiab Ntuj Eucommiae Foliuml Roj Qhov Tseem Ceeb Rau Kev Kho Mob ntawm daim tawv nqaij
Lignans thiab lawv cov derivatives yog cov khoom tseem ceeb ntawm EU [7]. Txog niaj hnub no, 28 lignans (xws li bisepoxylignans, monoepoxylignans, neolignans, thiab sesquilignans) tau raug cais tawm ntawm cov tawv ntoo, nplooj, thiab cov noob ntawm EU. Iridoid glycoside, chav kawm ntawm cov metabolites theem nrab, yog qhov thib ob tseem ceeb ntawm EU. Iridoids feem ntau pom muaj nyob hauv cov nroj tsuag hu ua glycosides. Nees nkaum plaub iridoids tau raug cais thiab txheeb xyuas los ntawm EU (Table 1). Cov tshuaj sib cais no suav nrog geniposidic acid, aucubin, thiab asperuloside uas tau tshaj tawm tias muaj cov khoom siv tshuaj dav dav [8-10]. Ob lub tebchaw tshiab ntawm iridoids, Eucommides-A thiab -C, tau raug cais tawm tsis ntev los no. Ob lub tebchaw ntuj no suav hais tias yog kev sib txuas ntawm iridoid thiab amino acids. Txawm li cas los xij, cov txheej txheem hauv qab lawv cov haujlwm tsis muaj [11].
2.2. Phenolic compounds
Phenolic compounds uas tau muab los ntawm cov khoom noj tau tshaj tawm tias muaj kev cuam tshuam zoo rau tib neeg kev noj qab haus huv [12,13]. Txog 29 phenolic tebchaw tau raug cais thiab txheeb xyuas los ntawm EU [14]. Tag nrho cov ntsiab lus ntawm phenolic tebchaw (hauv gallic acid sib npaug ntawm tag nrho cov extracts) tau soj ntsuam siv Folin-Ciocalteu phenol reagent. Cov teebmeem ntawm kev hloov pauv raws caij nyoog ntawm cov ntsiab lus ntawm qee cov tebchaw thiab cov tshuaj antioxidants tau tshaj tawm. Hauv tib lub xyoo, cov ntsiab lus siab dua ntawm phenolics thiab flavonoids tau pom nyob rau hauv nplooj ntawm EU thaum Lub Yim Hli thiab Tsib Hlis, raws li. Rutin, quercetin, geniposidic acid, thiab aucubin muaj nyob rau hauv siab dua nyob rau lub Tsib Hlis lossis Lub Rau Hli [15]. Ntxiv mus, ntau dua kev ua ntawm 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging kev ua si thiab hlau ion chelating muaj peev xwm tau pom nyob rau hauv nplooj ntawm EU sau nyob rau hauv lub yim hli ntuj. Ntxiv cov ntsiab lus ntawm cov zaub mov antioxidants kuj tau tshaj tawm nyob rau lub Tsib Hlis thaum piv rau lwm lub sijhawm ntawm lub xyoo [15]. Cov nplooj ntawm EU tau pom tias yog cov nplua nuj ntawm aminoacids, vitamins, minerals, thiab flavonoids xws li quercetin, rutin, thiab geniposidic acid [11,16]. Tag nrho ntawm 7 flavonoids tau raug cais tawm los ntawmEucommianroj tsuag [17]. Rutin thiab quercetin yog cov tseem ceeb tshaj plaws flavonoids [18]. Flavonoids yog cov sib txuas tseem ceeb uas muaj nyob hauv cov xwm txheej thiab raug suav tias yog cov metabolites theem nrab thiab ua haujlwm raws li cov neeg xa xov liaison, physiological regulators, thiab cell cycle inhibitors.
2.3. Steroids thiab Terpenoids
Rau steroids thiab tsib terpenoids tau muab rho tawm thiab categorized los ntawm EU. Cov no suav nrogβ-sitosterol, daucosterol, ulmoprenol, betalin, betulic acid, ursolic acid, eucommidiol, rehmaglutin C, thiab 1,4α,,5,7 ibα-tetrahydro-7-hydroxymethyl-cyclopenta[c]pyran-4-carboxylic methyl ester uas tau cais tshwj xeeb los ntawm cov tawv ntoo ntawm EU [19]. Loliolide kuj tau raug cais tawm ntawm nplooj [20].
2.4. Polysaccharides
Polysaccharides los ntawm EU rau 15 hnub ntawm qhov ntau ntawm 300-600 mg / kg tau tshaj tawm tias muaj kev tiv thaiv kev tiv thaiv ntawm lub raum raws li pom los ntawm malonaldehyde thiab glutathione qib tom qab lub raum perfusions [21]. Kev ntsuam xyuas histological kuj pom cov pov thawj ntawm cov khoom siv tshuaj tiv thaiv oxidative. Extracts los ntawm cov tawv ntoo ntawm EU siv 70% ethanol kuj pom muaj kev tiv thaiv tiv thaiv cadmium ntawm 125-500 mg / kg [22]. Kev soj ntsuam histological kuj pom tias EU ua ke nrogPanax pseudoginsengntawm 25% thiab 50% qhov hnyav, raws li, rau rau lub lis piam ntawm koob tshuaj ntawm 35.7-41.6 mg / kg tau siv lub teeb tiv thaiv ntawm glomerular filtration rate [8]. Ob lub polysaccharides tshiab tau raug cais tawm ntawm EU, uas yog eucomman A thiab B [23].
2.5. Lwm cov khoom xyaw thiab tshuaj
Amino acids, microelements, vitamins, thiab fatty acids kuj tau raug cais tawm los ntawm EU [17,21-23]. Sun et al. kuj pom cov tebchaw tshiab xws li n-octacosanoic acid, thiab tetracosanoic-2,3-dihydroxypropylester los ntawm EU [24].
Fatty acid muaj pes tsawg leeg ntawm cov roj muab rho tawm los ntawm cov noob ntawm EU tau pom qhov sib txawv ntawm polyunsaturated fatty acids xws li linoleic acid, linolenic acid (56.51% ntawm tag nrho cov fatty acids, TFAs), thiab linolelaidic acid (12.66% ntawm TFAs). Lub caij no, lub ntsiab monounsaturated fatty acid cais tawm ntawm cov noob tau pom tias yog isoleic acid (15.80% ntawm TFAs). Dominant saturated fatty acids cais muaj xws li palmitic acid thiab stearic acid uas sawv cev rau 9.82% thiab 2.59% ntawm TFAs, feem.